Unusual intracytoplasmic inclusions in metastatic carcinoma. Discussion of their possible significance

Autor:	U J, van Haelst, M, Pruszczynski
Rok vydání:	1995
Předmět:	Inclusion Bodies Male Microscopy Electron Carcinoma Acinar Cell Humans Retroperitoneal Neoplasms Aged
Zdroj:	Pathology, research and practice. 191(6)
ISSN:	0344-0338
Popis:	Unusual filamentous inclusion bodies in the cytoplasm of metastatic tumor cells are described. Their presence (intermingled with zymogen granules) seems rather restricted to cells of primary or metastatic acinar cell carcinoma of the pancreas, acinic carcinoma of salivary gland (parotid gland) and Paneth cells (neoplastic or in zinc deficiency state). For the time being, the real nature of these inclusions (deranged zymogen granules?) is unclear. This case also emphasizes the value of electron microscopy in solving the problem of the occult primary tumor and avoiding the misdiagnosis of an endocrine tumor (e.g. islet cell tumor or carcinoid), or a duct cell tumor with eosinophilic granular cytoplasm or in recognizing the foci of acinar cells in a mixed variant of carcinoma of the pancreas.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::1c8d20bb912e771ed72fa4ea525c1820 https://pubmed.ncbi.nlm.nih.gov/7479375 Zobrazit plný text záznamu Full Text from ScienceDirect