| Autor: |
Gouranga, Santra, Dibyendu, De, Pradip Kumar, Sinha |
| Rok vydání: |
2012 |
| Předmět: |
|
| Zdroj: |
The Journal of the Association of Physicians of India. 59 |
| ISSN: |
0004-5772 |
| Popis: |
Proximal renal tubular acidosis (pRTA) is a rare disorder. Hypokalemia may be associated with it; occasionally leading to features like hypokalemic periodic paralysis. Though pRTA is a tubulointerstitial kidney disease, glomerulonephritis may occasionally lead to pRTA by tubular damage through leaking proteins, cytokines or by inflammatory infiltrates. In our reported case a 27 year old male had recurrent episodes of hypokalemic quadriparesis. Investigations revealed features of pRTA including hypokalemia and non-anion-gap hyperchloremic metabolic acidosis. His urine pH dropped to 5 with NH4Cl loading test. Kidney biopsy showed membranoproliferative glomerulonephritis with tubulointerstitial damage. Hypokalemic periodic paralysis and pRTA are uncommon associations of membranoproliferative glomerulonephritis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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