[The expression of P-glycoprotein in leukemia P388 cells with induced doxorubicin resistance]

Autor:	V A, Sukhanov, V L, D'iakov, V V, Lalaev, A V, Iakh'iaev, I M, Voronkova, F V, Donenko, N B, Borovkova, L V, Moroz
Rok vydání:	1991
Předmět:	Gene Expression Regulation Neoplastic Membrane Glycoproteins Solubility Doxorubicin Leukemia P388 Immunoblotting Drug Resistance Animals ATP Binding Cassette Transporter Subfamily B Member 1 Chromatography Affinity Chromatography High Pressure Liquid Neoplasm Proteins
Zdroj:	Biulleten' eksperimental'noi biologii i meditsiny. 111(3)
ISSN:	0365-9615
Popis:	beta-D-galactose-containing glycoproteins were prepared from cells P-388 leukemia and from P-388 leukemia cells with induced resistance to doxorubicin. It was shown by HPLC method that plasma membranes from resistant cells contain 4-4.5% P-glycoproteins and plasma membranes from sensitive cells contain P-glycoproteins about 10 times lower.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::1c7ff8c77e6f68213cae63b427b8f9b9 https://pubmed.ncbi.nlm.nih.gov/1675897 Zobrazit plný text záznamu