Decline of humoral immune responses after natural SARS-CoV-2 infection can be efficiently reversed by vaccination

Autor: Fatma Betul, Oktelik, Vuslat, Yilmaz, Metin Yusuf, Gelmez, Nilgun, Akdeniz, Cevriye, Pamukcu, Tolga, Sutlu, Murat, Kose, Erdem, Tuzun, Gunnur, Deniz
Rok vydání: 2022
Předmět:
Zdroj: Canadian journal of microbiology. 68(8)
ISSN: 1480-3275
Popis: Our aim was to analyze severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific antibody level kinetics after coronavirus disease 2019 (COVID-19) infection and determine the efficiency of vaccination on SARS-CoV-2-specific antibody levels. The study included 50 SARS-CoV-2 infected and 70 uninfected cases. Levels of SARS-CoV-2-specific IgG nucleocapsid protein (IgG-NP), IgG spike protein (IgG-SP), IgM nucleocapsid protein (IgM-NP), and IgA spike protein (IgA-SP) antibodies were evaluated by an enzyme-linked immunosorbent assay in sera obtained at baseline, 1st, 3rd, and 6th month follow-up visits for infected cases and at postvaccination visits for all cases. In symptomatic cases (
Databáze: OpenAIRE