Arachidonic Acid and Nitroarachidonic: Effects on NADPH Oxidase Activity

Autor:	Lucía, Gonzalez-Perilli, Carolina, Prolo, María Noel, Álvarez
Rok vydání:	2019
Předmět:	Inflammation Arachidonic Acid Superoxides Macrophages NADPH Oxidase 2 Humans Phosphorylation Phosphoproteins Reactive Oxygen Species Reactive Nitrogen Species Respiratory Burst
Zdroj:	Advances in experimental medicine and biology. 1127
ISSN:	0065-2598
Popis:	Arachidonic acid (AA) is a polyunsaturated fatty acid that participates in the inflammatory response mainly through bioactive-lipids formation in macrophages and also in the phagocytic NADPH oxidase 2 (NOX2) activation. NOX2 is the enzyme responsible for a huge superoxide formation in macrophages, essential to eliminate pathogens inside the phagosome. The oxidase is an enzymatic complex comprised of a membrane-bound flavocytochrome b
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::1c5dc9aefb32d75071653edad5ff2e2f https://pubmed.ncbi.nlm.nih.gov/31140173 Zobrazit plný text záznamu