Interuncal distance as a measure of hippocampal atrophy: normative data on axial MR imaging

Autor: P M, Doraiswamy, W M, McDonald, L, Patterson, M M, Husain, G S, Figiel, O B, Boyko, K R, Krishnan
Rok vydání: 1993
Předmět:
Zdroj: AJNR Am J Neuroradiol
ISSN: 0195-6108
Popis: PURPOSE: To assess the effects of age and gender on the interuncal distance measured from MR images. METHODS: High-field strength MR images (axial) of 75 volunteers, 21-82 years old and free of neurologic disorders, were used to measure the interuncal distance. RESULTS: The interuncal distance increased with age (r = 0.66, P < .0001). The mean (SD) interuncal distance for all subjects was 21.4 (4) mm with a range of 12 to 29 mm. CONCLUSIONS: The interuncal distance in healthy subjects is unlikely to exceed 30 mm. Our data may be of clinical significance in view of a previous report stating that the interuncal distance may be enlarged in pathologic hippocampal degeneration, such as in patients with Alzheimer disease.
Databáze: OpenAIRE