Lack of association between immunoglobulin light-chain constant- and variable-region polymorphisms (C kappa, V kappa II, V lambda VII and VHIII) and rheumatoid arthritis

Autor:	D, Sidebottom, A S, Bate, D M, Grennan
Rok vydání:	1993
Předmět:	Arthritis Rheumatoid Immunoglobulin kappa-Chains Polymorphism Genetic Genes Immunoglobulin Immunoglobulin lambda-Chains Immunoglobulin Variable Region Humans Alleles Polymorphism Restriction Fragment Length
Zdroj:	Experimental and clinical immunogenetics. 10(3)
ISSN:	0254-9670
Popis:	Restriction fragment length polymorphisms (RFLPs) of C kappa, V kappa II, V lambda VII and VHIII genes were studied from a pool of 104 subjects with rheumatoid arthritis and 96 controls. There were no overall associations with either rheumatoid arthritis itself, or with HLA-DR4-positive and DR4-negative RA subgroups within rheumatoid subjects in this UK Caucasoid population.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::1bcf010a1c8f26411b186e5c83c697d5 https://pubmed.ncbi.nlm.nih.gov/7904455 Zobrazit plný text záznamu