| Autor: |
Xue-Bing, Ni, Xiao-Ming, Cui, Jin-Yue, Liu, Run-Ze, Ye, Yu-Qian, Wu, Jia-Fu, Jiang, Yi, Sun, Qian, Wang, Marcus Ho-Hin, Shum, Qiao-Cheng, Chang, Lin, Zhao, Xiao-Hu, Han, Ke, Ma, Shi-Jing, Shen, Ming-Zhu, Zhang, Wen-Bin, Guo, Jin-Guo, Zhu, Lin, Zhan, Liang-Jing, Li, Shu-Jun, Ding, Dai-Yun, Zhu, Jie, Zhang, Luo-Yuan, Xia, Xiang-Yong, Oong, Xiang-Dong, Ruan, Hong-Ze, Shao, Teng-Cheng, Que, Guang-Yuan, Liu, Chun-Hong, Du, En-Jiong, Huang, Xin, Wang, Li-Feng, Du, Chong-Cai, Wang, Wen-Qiang, Shi, Yu-Sheng, Pan, Yu-Hao, Zhou, Jiang-Li, Qu, Jiang, Ma, Cai-Wei, Gong, Qi-Qing, Chen, Qian, Qin, Tommy Tsan-Yuk, Lam, Na, Jia, Wu-Chun, Cao |
| Rok vydání: |
2022 |
| Zdroj: |
Nature microbiology. 8(1) |
| ISSN: |
2058-5276 |
| Popis: |
The increasing prevalence and expanding distribution of tick-borne viruses globally have raised health concerns, but the full repertoire of the tick virome has not been assessed. We sequenced the meta-transcriptomes of 31 different tick species in the Ixodidae and Argasidae families from across mainland China, and identified 724 RNA viruses with distinctive virome compositions among genera. A total of 1,801 assembled and complete or nearly complete viral genomes revealed an extensive diversity of genome architectures of tick-associated viruses, highlighting ticks as a reservoir of RNA viruses. We examined the phylogenies of different virus families to investigate virome evolution and found that the most diverse tick-associated viruses are positive-strand RNA virus families that demonstrate more ancient divergence than other arboviruses. Tick-specific viruses are often associated with only a few tick species, whereas virus clades that can infect vertebrates are found in a wider range of tick species. We hypothesize that tick viruses can exhibit both 'specialist' and 'generalist' evolutionary trends. We hope that our virome dataset will enable much-needed research on vertebrate-pathogenic tick-associated viruses. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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