Serological evidence of human Hantavirus infection in Argentina, Bolivia and Uruguay
| Autor: | M C, Weissenbacher, E, Cura, E L, Segura, M, Hortal, L J, Baek, Y K, Chu, H W, Lee |
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| Rok vydání: | 1996 |
| Předmět: |
Adult
Male Bolivia Orthohantavirus Adolescent Hantavirus Infections Argentina Infant Enzyme-Linked Immunosorbent Assay Middle Aged Antibodies Viral Rats Serology Neutralization Tests Paraguay Child Preschool Medical Laboratory Personnel Animals Humans Uruguay Female Child Fluorescent Antibody Technique Indirect Aged |
| Zdroj: | Medicina. 56(1) |
| ISSN: | 0025-7680 1985-1987 |
| Popis: | A serological survey was conducted in 1985-1987 to determine the presence of infection for Hantavirus in the general population in Argentina, Uruguay, Paraguay and Bolivia, as well as among rodent-exposed laboratory workers in Argentina. Out of 748 individuals tested by immunofluorescence 20 proved positive for Hantaan virus 76/118 strain of whom 16 also reacted against Seoul virus 80/39 strain and 2 against Puumala virus Sotkamo strain. Ten out of 72 Argentine laboratory workers were positive for the first 2 viruses by ELISA, immunofluorescence and/or plaque reduction neutralization test, in 4 of whom recent infection was demonstrated by IgM antibody presence. Inapparent Hantavirus infection was thus demonstrated for the first time in 2.7% of regional inhabitants, together with 13.9% among rodent-exposed laboratory workers. Our data established the existence of human Hantavirus infection nearly 10 years before the recognition of clinical cases of hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome in Argentina. |
| Databáze: | OpenAIRE |
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