[Antitumor activity of Ca-double-stranded RNA from sodium nucleinate]

Autor: R A, Zakharian, N P, Mespropian, A V, Movsesian, A S, Agabalian, Zh I, Akopian
Rok vydání: 1985
Předmět:
Zdroj: Eksperimental'naia onkologiia. 7(3)
ISSN: 0204-3564
Popis: Ca-dsRNA introduced in the concentration of 5 micrograms per mouse 24 hours before the MG22a mouse hepatoma transplantation causes the 70% inhibition of the hepatoma growth. The sodium nucleinate used in the considerably higher concentration had a less effect. The sodium form of dsRNA also had a less antitumour effect comparing with its calcium form. The calcium form of dsRNA proves to be relatively stable and physiologically active form of dsRNA during its parenteral administration.
Databáze: OpenAIRE