| Autor: |
Suzanne, Veldhuis, Richard, van Altena, Reindert P, van Steenwijk, Erik A J, Rauws, Jan Karel M, Eeftinck Schattenkerk |
| Jazyk: |
Dutch; Flemish |
| Rok vydání: |
2013 |
| Předmět: |
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| Zdroj: |
Nederlands tijdschrift voor geneeskunde. 157(22) |
| ISSN: |
1876-8784 |
| Popis: |
Multidrug-resistant tuberculosis is increasing worldwide. The determination of possible resistance is essential for adequate treatment. Tuberculosis is common amongst immigrants from Somalia and extra-pulmonary localisation is often seen.A 21-year-old woman from Somalia presented with progressive dysphagia and severe weight loss. Endoscopy revealed two ulcers in the mid-oesophagus. A chest x-ray showed enlarged lymph nodes in the right hilar and mediastinal regions. The Ziehl-Neelsen stain and PCR for mycobacteria were negative. Sputum samples and oesophageal biopsies were cultured. Quadruple tuberculostatic therapy was started empirically. After five weeks, a sputum culture grew Mycobacterium tuberculosis, which was resistant to rifampicin and isoniazid. She was treated with second-line anti-tuberculous therapy and eventually recovered.Tuberculosis can manifest in many ways. It is important to obtain patient material for culture; not only to confirm the diagnosis but also for the determination of possible resistance which is necessary for adequate therapy. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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