| Autor: |
Noriyuki, Ohno, Makoto, Ishida, Kenji, Ohnishi, Katsuji, Sawai, Shinsuke, Tabata, Masaaki, Deguchi, Tatsumi, Kitajima, Yasuharu, Kaizaki |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Gan to kagaku ryoho. Cancerchemotherapy. 44(12) |
| ISSN: |
0385-0684 |
| Popis: |
We report a resected case with a pathological complete response(pCR)after neoadjuvant chemotherapy for borderline resectable pancreatic cancer(BRPC). A 67-year-old woman who had been treated for type 2 diabetes mellitus in our hospital presented with an exacerbation of diabetes. An abdominal CT scan confirmed a hypovascular mass in the pancreas body consistent with BRPC. After 3 courses of chemotherapy with gemcitabine plus nab-paclitaxel(GnP), her elevated DUPAN-2 level normalized. A follow up CT scan revealed that the tumor had decreased in size, and no distant metastasis was detected. Distal pancreatectomy with en-bloc celiac axis resection was performed. Histopathological examination of the resected specimens showed no evidence of residual cancer cells(pCR). The patient remains disease-free 8 months after surgery. Neoadjuvant GnP chemotherapy may be useful for BRPC. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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