Autor: |
Naoya, Shimada, Yukiko, Okuda, Kaisei, Maeda, Daisuke, Umeno, Shinichi, Takaichi, Masahiko, Ikeuchi |
Rok vydání: |
2020 |
Předmět: |
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Zdroj: |
The Journal of general and applied microbiology. 66(2) |
ISSN: |
1349-8037 |
Popis: |
Heterologous production of a useful carotenoid astaxanthin was achieved in a cyanobacterium Synechocystis sp. PCC 6803 with the aid of marine bacterial genes. Astaxanthin and its intermediates emerged at high levels, whereas β-carotene and zeaxanthin disappeared in the strain. Total carotenoid accumulation was nearly two fold compared with wild type. The astaxanthin-producing strain was capable of only growing heterotrophically, which was likely due to the absence of β-carotene. Further enhanced accumulation was pursued by gene overexpression for possible rate-limiting steps in the biosynthesis pathway. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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