Autor: |
N V, Gorbunov, R A, Nasyrov, A N, Erin, V P, Ivanova, L Iu, Taros |
Rok vydání: |
1992 |
Předmět: |
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Zdroj: |
Biulleten' eksperimental'noi biologii i meditsiny. 113(6) |
ISSN: |
0365-9615 |
Popis: |
The effect of various concentrations of both methyl ether of 5-doxyl-stearic acid (M5DS) and 4-maleimido-TEMPO (4MT) on the pathogenicity of herpes simplex virus (HSV-1) was studied. It is known that the reagents modify the lipid matrix and the proteins of virion envelope. The decrease of the HSV-1 pathogenicity was shown when using the concentration of reagents more 5 x 10(-5) M. HSV-1 having high pathogenicity and cytotoxicity was obtained when the concentrations of the reagents were less 5 x 10(-5) M. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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