| Autor: |
Guillermo, Luna-Nevarez, Amy C, Kelly, Leticia E, Camacho, Sean W, Limesand, Javier R, Reyna-Granados, Pablo, Luna-Nevarez |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Tropical animal health and production. 52(6) |
| ISSN: |
1573-7438 |
| Popis: |
Sheep production in desert environments during summer is challenging due to heat stress which reduces feed intake, growth, and fertility. Despite warm conditions, some ewes are able to maintain a normal performance suggesting the existence of genetic bases underlying heat tolerance. Our objective was to discover and validate genetic markers associated with thermo-tolerance in pregnant ewes exposed to warm environmental conditions. Using a well-defined model laboratory of heat stress in sheep, pregnant Columbia-Rambouillet crossbred ewes (n = 100) were examined. Following acclimation to the laboratory at thermo-neutral conditions, heat stress was induced in ewes by increasing the temperature-humidity index in a control environmental chamber during mid-gestation. Feed intake, water consumption, and rectal temperature were recorded daily and used to establish the heat stress tolerance index (HSTI) for each ewe. Rectal temperature was a predictor (P 0.05) of feed intake, and the regression coefficient was used to classify the HSTI. In a subset of 24 ewes, a genome-wide association study (GWAS) was performed using the Illumina OvineSNP50 BeadChip. Single-marker analysis detected 3 intragenic SNPs associated with HSTI (P value = 10 |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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