[Oxidized fibrinogen and its relationship with hemostasis disturbances and endothelial dysfunction during coronary heart disease and myocardial infarction]

Autor:	Iu I, Ragino, V A, Baum, Ia V, Polonskaia, S R, Baum, Iu P, Nikitin
Rok vydání:	2009
Předmět:	Adult Male Hemostasis Platelet Aggregation Myocardial Infarction Fibrinogen Coronary Artery Disease Blood Coagulation Disorders Middle Aged Prognosis Vasodilation Humans Endothelium Vascular Lipid Peroxidation Oxidation-Reduction Aged
Zdroj:	Kardiologiia. 49(9)
ISSN:	0022-9040
Popis:	The highest oxidative modification of fibrinogen was found in acute myocardial infarction (MI) men and it was 1.26 and 1.56 times higher in comparison with coronary heart disease (CHD) men with anamnesis of MI and with men without CHD, respectively. Increased oxidized fibrinogen level correlated with increased levels of plasma lipid peroxidation products, Willebrand factor, fibrin degradation products, accelerated leukocyte-platelet aggregation and decreased level of plasma NO metabolites. Associations of oxidized fibrinogen with MI and typical parameters of thrombosis and hypercoagulatory hemostasis disturbances and endothelial function were revealed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::1ac4159d4badf7fef5f506914eb39c20 https://pubmed.ncbi.nlm.nih.gov/19772496 Zobrazit plný text záznamu