| Autor: |
L P, Kurochkina, A A, Komissarov, G Ia, Kolomiĭtseva |
| Rok vydání: |
1987 |
| Předmět: |
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| Zdroj: |
Biokhimiia (Moscow, Russia). 52(10) |
| ISSN: |
0320-9725 |
| Popis: |
A thymine-modified derivative of histone H3 formed as a result of thermal treatment of UV-irradiated (lambda = 254 nm) solution of deoxyribonucleoprotein from calf thymus at low ionic strength was isolated. The peptides obtained by tryptic hydrolysis of modified histone H3 were separated by high pressure liquid chromatography. The amino acid sequence of the peptide containing a lysine residue with covalently linked thymine was determined by the Edman method. It was found that Lys localized at the N-terminus of the histone H3 molecule interacts with DNA within the composition of the deoxyribonucleoprotein. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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