Para-aminobenzoate inhibition of precipitation of urine salts

Autor: C J, Zarafonetis, J G, Batsakis, R A, Wolfe
Rok vydání: 1979
Předmět:
Zdroj: Research communications in chemical pathology and pharmacology. 23(2)
ISSN: 0034-5164
Popis: Lehmann's observation that potassium para-aminobenzoate has a "salt precipitating preventive effect" in urine was confirmed in rats. This effect persisted during the 3-week period of drug administration. There was associated no significant change in urine volume, osmolality, or per cent solids. Since there is a large clinical experience in the chronic use of even larger doses, it would appear quite feasible to determine the clinical usefulness of this property of para-aminobenzoate in the prevention of recurrent renal calculi.
Databáze: OpenAIRE