Field evaluation of latex agglutination test for detecting urinary antigens in visceral leishmaniasis in Sudan
| Autor: | S H, El-Safi, A, Abdel-Haleem, A, Hammad, I, El-Basha, A, Omer, H G, Kareem, M, Boelaert, M, Chance, M, Hommel |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Adolescent Endemic Diseases Immunoblotting Infant Antigens Protozoan Enzyme-Linked Immunosorbent Assay Middle Aged Prognosis Sensitivity and Specificity Sudan Case-Control Studies Child Preschool Animals Humans Leishmaniasis Visceral Female Parasitology Child Fluorescent Antibody Technique Indirect Latex Fixation Tests Leishmania donovani |
| Zdroj: | Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit. 9(4) |
| ISSN: | 1020-3397 |
| Popis: | A latex agglutination test to detect urinary antigens for visceral leishmaniasis (VL) was studied. In 204 patients with suspected VL, KAtex had a sensitivity of 95.2% with good agreement with microscopy smears but poor agreement with 4 different serology tests. It was also positive in 2 confirmed VL cases co-infected with HIV. In all K4tex-positive confirmed cases actively followed up after treatment, the test became negative 1 month after completion of treatment. While IC4tex had a specificity of 100% in healthy endemic and non-endemic controls, the direct agglutination test (DAT) was positive in 14% of the KAtex-negative healthy endemic controls. KAtex is a simple addition to the diagnostics of VL particularly at field level and as a complementary test for the diagnosis of VL in smear-negative cases with positive DAT results. |
| Databáze: | OpenAIRE |
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