Airspace dimension assessment with nanoparticles as a proposed biomarker for emphysema

Autor: H Laura, Aaltonen, Madeleine, Petersson Sjögren, Jonas K F, Jakobsson, Hanna, Nicklasson, Sandra, Diaz, Francisco, Sánchez Montiel, Sophia, Zackrisson, Veronica, Ideböhn, Gunnar, Engström, Jakob, Löndahl, Per, Wollmer
Rok vydání: 2020
Předmět:
Zdroj: Thorax
ISSN: 1468-3296
Popis: Airspace dimension assessment with nanoparticles (AiDA) is a novel method to measure distal airspace radius non-invasively. In this study, AiDA radii were measured in 618 individuals from the population-based Swedish CArdiopulmonary BioImaging Study, SCAPIS. Subjects with emphysema detected by computed tomography were compared to non-emphysematous subjects. The 47 individuals with mainly mild-to-moderate visually detected emphysema had significantly larger AiDA radii, compared with non-emphysematous subjects (326±48 µm vs 291±36 µm); OR for emphysema per 10 µm: 1.22 (1.13–1.30, p
Databáze: OpenAIRE