| Autor: |
B J, Morland, J R, Mann, D V, Milford, F, Raafat, M C, Stevens |
| Rok vydání: |
1996 |
| Předmět: |
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| Zdroj: |
Medical and pediatric oncology. 27(1) |
| ISSN: |
0098-1532 |
| Popis: |
We report on two children with rhabdomyosarcoma who received ifosfamide as part of their chemotherapy schedule. Both children subsequently developed severe ifosfamide-induced nephrotoxicity, necessitating electrolyte supplementation. We describe the histopathological findings of renal biopsies performed in these children after the onset of renal dysfunction and comment on the possible mechanisms involved in ifosfamide nephrotoxicity. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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