Rational design of new multitarget histamine H

Autor:	Dorota, Łażewska, Marek, Bajda, Maria, Kaleta, Paula, Zaręba, Agata, Doroz-Płonka, Agata, Siwek, Alaa, Alachkar, Szczepan, Mogilski, Ali, Saad, Kamil, Kuder, Agnieszka, Olejarz-Maciej, Justyna, Godyń, Dorota, Stary, Sylwia, Sudoł, Małgorzata, Więcek, Gniewomir, Latacz, Maria, Walczak, Jadwiga, Handzlik, Bassem, Sadek, Barbara, Malawska, Katarzyna, Kieć-Kononowicz
Rok vydání:	2020
Předmět:	Male Molecular Docking Simulation Mice Monoamine Oxidase Inhibitors Alzheimer Disease Protein Conformation Drug Design Animals Humans Receptors Histamine H3 Cholinesterase Inhibitors Molecular Targeted Therapy Ligands
Zdroj:	European journal of medicinal chemistry. 207
ISSN:	1768-3254
Popis:	Design and development of multitarget-directed ligands (MTDLs) has become a very important approach in the search of new therapies for Alzheimer's disease (AD). In our present research, a number of xanthone derivatives were first designed using a pharmacophore model for histamine H
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::19b9ce0cd6668a224d31e97fea8dca07 https://pubmed.ncbi.nlm.nih.gov/32882609 Zobrazit plný text záznamu Full Text from ScienceDirect