| Autor: |
Mate, Kozma, Mariann, Bombicz, Balazs, Varga, Daniel, Priksz, Rudolf, Gesztelyi, Vera, Tarjanyi, Rita, Kiss, Reka, Szekeres, Barbara, Takacs, Akos, Menes, Jozsef, Balla, Gyorgy, Balla, Judit, Szilvassy, Zoltan, Szilvassy, Bela, Juhasz |
| Rok vydání: |
2021 |
| Zdroj: |
Pharmaceutics. 14(2) |
| ISSN: |
1999-4923 |
| Popis: |
Impaired mitochondrial function is associated with several metabolic diseases and health conditions, including insulin resistance and type 2 diabetes (T2DM), as well as ageing. The close relationship between the above-mentioned diseases and cardiovascular disease (CVD) (diabetic cardiomyopathy and age-related cardiovascular diseases) has long been known. Mitochondria have a crucial role: they are a primary source of energy produced in the form of ATP via fatty acid oxidation, tricarboxylic acid (TCA) cycle, and electron transport chain (ETC), and ATP synthase acts as a key regulator of cardiomyocyte survival. Mitochondrial medicine has been increasingly discussed as a promising therapeutic approach in the treatment of CVD. It is well known that vitamin B3 as an NAD |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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