Autor: |
Y I, Ronin, A B, Korol, T, Fahima, V M, Kirzhner, E, Nevo |
Rok vydání: |
1996 |
Předmět: |
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Zdroj: |
Biometrics. 52(4) |
ISSN: |
0006-341X |
Popis: |
PCR-based markers are used for targeting plant genes. However, mapping these markers requires laborious and expensive analysis of individual genotypes. We propose here a sequential procedure for fine mapping of PCR markers relative to a target gene. Stepwise bulked analysis is employed to get a censored estimation of the recombination rate. The sequential estimation is compared to fixed sample size design. In both cases, the proposed procedure can achieve a substantial reduction in the number of PCR runs (up to 90-97% for close linkage) as compared to the standard individual-by-individual analysis. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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