NHR-8 and P-glycoproteins uncouple xenobiotic resistance from longevity in chemosensory
| Autor: | Gabriel A, Guerrero, Maxime J, Derisbourg, Felix Amc, Mayr, Laura E, Wester, Marco, Giorda, J Eike, Dinort, Matías D, Hartman, Klara, Schilling, María José, Alonso-De Gennaro, Ryan J, Lu, Bérénice A, Benayoun, Martin S, Denzel |
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| Rok vydání: | 2019 |
| Předmět: |
ATP Binding Cassette Transporter
Subfamily B Time Factors Tunicamycin Longevity Drug Resistance Kinesins Receptors Cytoplasmic and Nuclear Forkhead Transcription Factors Endoplasmic Reticulum Stress Animals Genetically Modified Gene Expression Regulation Mutation Animals Mitogen-Activated Protein Kinases Caenorhabditis elegans Caenorhabditis elegans Proteins |
| Zdroj: | eLife. 10 |
| ISSN: | 2050-084X |
| Popis: | Longevity is often associated with stress resistance, but whether they are causally linked is incompletely understood. Here we investigate chemosensory-defective |
| Databáze: | OpenAIRE |
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