[Clinical analysis of 51 cases of oral mucosal melanoma]
| Autor: | Chuan-zheng, Sun, Fu-jin, Chen, Ming, Song, Yu-e, Jiang, An-kui, Yang, Yan-feng, Chen |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adult
Male Lung Neoplasms S100 Proteins Mouth Mucosa Middle Aged Combined Modality Therapy Survival Rate Interferon-gamma Lymphatic Metastasis Antineoplastic Combined Chemotherapy Protocols BCG Vaccine Humans Interleukin-2 Lymph Node Excision Female Mouth Neoplasms Melanoma Melanoma-Specific Antigens Aged Follow-Up Studies Retrospective Studies gp100 Melanoma Antigen |
| Zdroj: | Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology. 46(9) |
| ISSN: | 1002-0098 |
| Popis: | To investigate the treatment and prognosis of the patients with oral mucosal melanoma (OMM).The clinicopathological and follow-up data of patients with OMM in Sun Yat-sen University Cancer Center from January 1976 to December 2005 were analyzed retrospectively.Fifty-one cases were analyzed. The pathological lymph node metastasis rate was 61% (31/51) and the affected sites were confined to level I(b)-III (94%). The overall three year and five yearsurvival rates were 35% and 21% respectively. No significant difference of three year and five year survival rates were found between the group of incisional biopsy and the group of excisional biopsy. The prognosis was not affected by pigmentation. The survival rate of the patients receiving surgery combined with biotherapy or biochemotherapy was significantly higher than that of the patients treated by other modalities (P = 0.003).In patients with OMM, lymph node metastasis was mostly confined to level I(b)-III. Incisional biopsy and pigmentation were not associated with an unfavorable prognosis. The prognosis of the patients with OMM was poor and the patients may get a better prognosis by receiving surgery combined with biotherapy or biochemotherapy. |
| Databáze: | OpenAIRE |
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