Analysis of a 62 kb DNA sequence of chromosome X reveals 36 open reading frames and a gene cluster with a counterpart on chromosome XI
| Autor: | M E, Huang, V, Manus, J C, Chuat, F, Galibert |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
mRNA Cleavage and Polyadenylation Factors
Saccharomyces cerevisiae Proteins Base Sequence Sequence Homology Amino Acid Genes Fungal Molecular Sequence Data RNA-Binding Proteins Saccharomyces cerevisiae Sequence Analysis DNA DNA-Binding Proteins Fungal Proteins Open Reading Frames RNA Transfer Multigene Family Nucleic Acid Conformation Amino Acid Sequence Chromosomes Fungal DNA Fungal |
| Zdroj: | Yeast (Chichester, England). 12(9) |
| ISSN: | 0749-503X |
| Popis: | We have sequenced a 61.989 bp stretch located between genes RAD7 and FIP1 of Saccharomyces cerevisiae chromosome X. This stretch contains 36 open reading frames (ORFs) of at least 100 codons. Fourteen of these correspond to sequences previously published as HIT1, CDC8, YAP17, CBF1, NAT1, RPA12, CCT5, TOR1, RFC2, PEM2, CDC11, MIR1, STE18 and GRR1. The proteins deduced from four ORFs (YJR059w, YJR065c, YJR075w, YJR078w) have significant similarity to proteins of known function from yeast or other organisms, including S. cerevisiae serine/threonine-specific protein kinase. Schizosaccharomyces pombe Act2 protein, S. cerevisiae mannosyltransferase OCH1 protein and mouse indoleamine 2,3-dioxygenase, respectively. Four of the remaining 18 ORFs have similarity to proteins with unknown function, six are weakly similar to other known sequences, while another eight exhibit no similarity to any known sequence. In addition, three tRNA genes have been recognized. Three genes clustered within 22 kb (YJR059w, YJR061w and TOR1) have counterparts arranged within 15 kb on the left arm of chromosome XI. |
| Databáze: | OpenAIRE |
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