[Iminodimethylation, a method for pharmacomodulation in pyrimido-[3,4-a]-s-triazine series]

Autor: S, Menager, C, Loire, T, Petrakian, C, Combet Farnoux, C, Delabos, J, Garnier, O, Lafont
Jazyk: francouzština
Rok vydání: 1995
Předmět:
Zdroj: Annales pharmaceutiques francaises. 53(1)
ISSN: 0003-4509
Popis: Primary amines react with two formaldehydes and compounds presenting two mobile hydrogen atoms, this reaction can be called iminodimethylation. This reaction can be used in order to perform a pharmacomodulation in the pyrimido [3,4-a]-s-triazine series. Against Epidermophyton floccosum, the activity is better when nitrogen 7 is not substituted, when the heroatom in position 2 is 0 instead of S and when an aromatic nucleus is directly linked to the nitrogen atom in position 3.
Databáze: OpenAIRE