[Monoclonal antibodies against D-antigen of the rhesus system]

Autor: N I, Olovnikova, E I, Deriugina
Rok vydání: 1993
Předmět:
Zdroj: Gematologiia i transfuziologiia. 38(7)
ISSN: 0234-5730
Popis: The authors review current data on the production and characterization of anti-D monoclonal antibodies. The main methods for establishment of anti-D antibody secreting cell lines are considered: EBV-transformation of B lymphocytes from immune donor and hybridization with malignant human or murine cell lines. Serologic and immunological properties of anti-D monoclonal reagents for blood group Rh-typing as well as feasibility of using anti-D monoclonal antibodies as a modality against hemolytic disease of the newborn are discussed.
Databáze: OpenAIRE