Autor: |
S G, Markushin, N A, Kantarov, S V, Artiushenko, I I, Akopova, I B, Koptiaeva, Iu N, Bubnov |
Rok vydání: |
2011 |
Předmět: |
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Zdroj: |
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 56(5-6) |
ISSN: |
0235-2990 |
Popis: |
Comparative investigation of the virus-inhibiting activity of some boron-containing compounds showed that products BG 12 and BG 4 had the highest inhibitory effect on pandemic viruses. The minimum inhibitory concentration (MIC) of the products was 0.1 mcg/ml. The use of liposomes loaded with BG 12 molecules in the optimal concentration (0.1 mcg/ml) resulted in inhibition of the avian plague virus growth in the MDCK cells. Possible design of efficient drugs for antiviral protection based on the complexes liposomes--boron-containing compounds is discussed. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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