Population-based survey of hepatitis A virus infection in the Republic of San Marino

Autor: T, Stroffolini, S, Pretolani, F, Miglio, M, Rapicetta, U, Villano, F, Bonvicini, L, Baldini, F, Sampogna, G, Giulianelli, M L, Stefanelli, A, Carloni, A, Sorcinelli, G, Ghironzi, G, Gasbarrini
Rok vydání: 1997
Předmět:
Zdroj: European journal of epidemiology. 13(6)
ISSN: 0393-2990
Popis: In 1990-1991, the prevalence of antibodies to hepatitis A virus infection (anti-HAV) was assayed by the ELISA method among 1528 apparently healthy subjects, 20-85 years old in the Republic of San Marino. Subjects were selected from the list of residents by a random stratified sampling procedure with a proportional allocation by age, sex and district of residence. The overall anti-HAV prevalence was 64.7%; it increased from 28.6% in subjects 20-30 years old to 97% in those60 years (p0.01). No gender difference was observed. At the multivariate analysis age40 years (OR: 39.5; 95% CI: 12.4-126) and lowest level of schooling (OR: 1.8; 95% CI: 1.1-2.9), which is a good indirect indicator of socio-economic status, resulted both independent predictors of anti-HAV seropositivity. These findings reflect the improved sanitation standards in this area and indicate that the proportion of non-immune adults is increasing with a higher risk of symptomatic infection in the near future.
Databáze: OpenAIRE