[Infection of repair-deficient human cells by the vaccinia virus decreases the formation of gamma-induced DNA breaks]

Autor: T A, Sinel'shchikova, E G, Gubitskaia, N B, Akhmatullina, G D, Zasukhina
Rok vydání: 1990
Předmět:
Zdroj: Radiobiologiia. 30(6)
ISSN: 0033-8192
Popis: The alkaline elution method was used to study DNA breaks induced by the different mutagens in human cells. Normal fibroblasts and fibroblasts from patients with homocystinuria, deficient in gamma-type repair were shown to be resistant to gamma-radiation after the vaccinia virus infection. In both cell lines there was a decrease in the number of the mutagen-induced DNA breaks.
Databáze: OpenAIRE