| Autor: |
L N, Tarasova, O Iu, Skol'skaia, S G, Vladimirova |
| Rok vydání: |
2011 |
| Předmět: |
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| Zdroj: |
Terapevticheskii arkhiv. 83(7) |
| ISSN: |
0040-3660 |
| Popis: |
The review presents modern conceptions of disturbances in endothelial lining of the vessels and plasmic hemostasis in patients with acute leukemia; different mechanisms of coagulation disorders in acute leukemia: effects of leukemic cells containing procoagulants, fibrinolytic and antifibrinolytic substances, of intensive chemotherapy and inflammation. All these impacts impair endothelial cells and trigger plasmic coagulation cascade; the initiator of coagulation is a tissue factor. Mechanisms of this process and statistics of thrombohemorrhagic complications in different variants of acute leukemia are outlined. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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