| Autor: |
D, Tanne, V E, Bates, P, Verro, S E, Kasner, J R, Binder, S C, Patel, H H, Mansbach, S, Daley, L R, Schultz, P N, Karanjia, P, Scott, J M, Dayno, K, Vereczkey-Porter, C, Benesch, D, Book, W M, Coplin, D, Dulli, S R, Levine |
| Rok vydání: |
1999 |
| Předmět: |
|
| Zdroj: |
Neurology. 53(2) |
| ISSN: |
0028-3878 |
| Popis: |
We assessed initial clinical experience with IV tissue plasminogen activator (t-PA) treatment of acute ischemic stroke in a standardized retrospective survey of hospitals with experienced acute stroke treatment systems. The incidence of symptomatic intracerebral hemorrhage (ICH) was 6% (11 of 189 patients; 95% CI 3 to 11%), similar to that in the National Institute of Neurological Disorders and Stroke (NINDS) t-PA Stroke Study. Deviations from the NINDS protocol guidelines were identified in 30% of patients (56 of 189). The incidence of symptomatic ICH was 11% among patients with protocol deviations as compared with 4% in patients who were treated according to the NINDS protocol guidelines, suggesting that strict adherence to protocol guidelines is prudent. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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