| Autor: |
Ezekiel Uba, Nwose, Nathan, Cann, Eugene, Butkowski |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
North American Journal of Medical Sciences |
| ISSN: |
1947-2714 |
| Popis: |
Background: Anticoagulant and antiplatelet therapies are being used interchangeably or in combination. While international normalized ratio is assessed to determine anticoagulant's contraindication/need, whole blood viscosity is not assessed to determine the need for antiplatelet. Aims: The objective of this study is to investigate whether whole blood viscosity value is associated with levels of international normalized ratio and platelet count. Materials and Methods: De-identified archived clinical pathology data for the year 2008 were audited. All cases of international normalized ratio, which were concomitantly tested for haematocrit and total proteins, were extracted (n=7,387). Whole blood viscosity levels were extrapolated. Whether differences are associated with normal vs. high international normalized ratio and thrombocytopenia vs. thrombocytosis were evaluated. Results: Multivariate analysis show that whole blood viscosity levels statistically significantly differs between international normalized ratio and platelet counts (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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