| Autor: |
S K, Pirutin, V B, Turovetskiĭ, A B, Druzhko, Iu B, Kudriashov |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
Radiatsionnaia biologiia, radioecologiia. 53(6) |
| ISSN: |
0869-8031 |
| Popis: |
In this paper we showed the pH-dependent change in the sensitivity of the membranes of murine peritoneal macrophages to UV-radiation. This relationship is discussed in terms of lipid bilayer membrane stability modification to the action of ROS and lipid peroxidation process (LPP) at different pH. Iron-ascorbate reinforced LPP also led to pH-dependent membranes damage. The increase of the cells incubation medium temperature up to 37 degrees C, which also stimulated LPP, did not change the picture of the pH-dependent damage. Decrease of the incubation medium pH did not reduce H2O2-induced cell damage. Increase of the pH intensified the cells damage. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
