Altered Circulating Follicular T Helper Cell Subsets and Follicular T Regulatory Cells Are Indicators of a Derailed B Cell Response in Lupus, Which Could Be Modified by Targeting IL-21R

Autor: Krisztina, Szabó, Ilona, Jámbor, Kitti, Pázmándi, Nikolett, Nagy, Gábor, Papp, Tünde, Tarr
Rok vydání: 2022
Předmět:
Zdroj: International journal of molecular sciences. 23(20)
ISSN: 1422-0067
Popis: Systemic lupus erythematosus (SLE) is characterized by the breakdown of self-tolerance, the production of high-affinity pathogenic autoantibodies and derailed B cell responses, which indicates the importance of central players, such as follicular T helper (T
Databáze: OpenAIRE
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