Modifications to central neural circuitry during heart failure

Autor:	M L, Weiss, M J, Kenney, T I, Musch, K P, Patel
Rok vydání:	2002
Předmět:	Neurons Neurotransmitter Agents Ganglia Sympathetic Sympathetic Nervous System Cardiac Output Low Brain Autonomic Nervous System Kidney Efferent Pathways Rats Renin-Angiotensin System Animals Humans Paraventricular Hypothalamic Nucleus
Zdroj:	Acta physiologica Scandinavica. 177(1)
ISSN:	0001-6772
Popis:	During heart failure (HF), excess sodium retention is triggered by increased plasma renin-angiotensin-aldosterone activity and increased basal sympathetic nerve discharge (SND). Enhanced basal SND in the renal nerves plays a role in sodium retention. Therefore, as a hypothetical model for the central sympathetic control pathways that are dysregulated as a consequence of HF, the central neural pathways regulating the sympathetic motor output to the kidney are reviewed in the context of their role during HF.From these findings, a model of the neuroanatomical circuitry that may be affected during HF is constructed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::153a012379a53662db8a4b24fe0519f9 https://pubmed.ncbi.nlm.nih.gov/12492779 Zobrazit plný text záznamu Plný text