| Autor: |
L, Chedid, G M, Bahr, F Z, Modabber, C A, Dinarello, S M, Wolff |
| Jazyk: |
francouzština |
| Rok vydání: |
1983 |
| Předmět: |
|
| Zdroj: |
Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie. 297(4) |
| ISSN: |
0249-6313 |
| Popis: |
A monoclonal anti-MDP antibody was found to bind to "Slow Wave Sleep" factor. This result confirms that this factor is a muramyl peptide and furthermore shows that it contains a structure characteristic of the synthetic adjuvant and of the bacterial cell wall, i.e. an acetylated muramic acid bound to L-alanine. This antibody was also shown to specifically inhibit a biological activity of a purified human monokine which induces fever. Because of these results and other recent observations we propose that a bacterial structure is present in certain mammalian mediators. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
