| Autor: |
S L, Carmichael, C, Ma, S A, Rasmussen, M L, Cunningham, M L, Browne, C, Dosiou, E J, Lammer, G M, Shaw |
| Rok vydání: |
2014 |
| Předmět: |
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| Zdroj: |
American journal of medical genetics. Part A. (4) |
| ISSN: |
1552-4833 |
| Popis: |
Thyroid disease is a common problem among women of reproductive age but often goes undiagnosed. Maternal thyroid disease has been associated with increased risk of craniosynostosis. We hypothesized that known risk factors for thyroid disease would be associated with risk of craniosynostosis among women not diagnosed with thyroid disease. Analyses included mothers of 1,067 cases and 8,494 population-based controls who were interviewed for the National Birth Defects Prevention Study. We used multivariable logistic regression to estimate adjusted odds ratios (AOR) and 95% confidence intervals (CI). After excluding women with diagnosed thyroid disease, younger maternal age (AOR 0.7, 95% CI 0.6–0.9, for |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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