CRL4

Autor: Xiao-Ran, Han, Naoya, Sasaki, Sarah C, Jackson, Pu, Wang, Zhijun, Li, Matthew D, Smith, Ling, Xie, Xian, Chen, Yanping, Zhang, William F, Marzluff, Yue, Xiong
Rok vydání: 2020
Předmět:
Zdroj: Science advances. 6(51)
ISSN: 2375-2548
Popis: Evolutionarily conserved DCAF1 is a major substrate receptor for the DDB1-CUL4-ROC1 E3 ubiquitin ligase (CRL4) and controls cell proliferation and development. The molecular basis for these functions is unclear. We show here that
Databáze: OpenAIRE