Effects of mesh modification on the structure of a mandrel-grown biosynthetic vascular prosthesis

Autor:	J A, Ramshaw, F, Casagranda, J F, White, G A, Edwards, J A, Hunt, D F, Williams, J A, Werkmeister
Rok vydání:	1999
Předmět:	Microscopy Electron Sheep Heparin Polyesters Microscopy Electron Scanning Animals Biocompatible Materials Serum Albumin Bovine Collagen Dexamethasone Fluorescein-5-isothiocyanate Blood Vessel Prosthesis
Zdroj:	Journal of biomedical materials research. 47(3)
ISSN:	0021-9304
Popis:	Mandrel-grown, mesh-reinforced vascular prostheses require adequate tissue coverage of the mesh for effective clinical function, particularly in low blood flow situations. Development of the ovine collagen-based Omniflowtrade mark vascular prosthesis has shown that the extent of this tissue cover is dependent on the interactions of the mandrel and the mesh with the sheep host. In the present study, the effects of chemical changes to the mesh have been examined. These data indicate that certain treatments of the mesh, particularly collagen or heparin, lead to increased tissue coverage while the number of sheep cells present and the ultrastructure of the resulting vessel remain unchanged.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::13a94947833fbcf4fa8765963e89761a https://pubmed.ncbi.nlm.nih.gov/10487881 Zobrazit plný text záznamu Plný text