| Autor: |
R, Gai, A, Oliaro, F, Galietti, G E, Giorgis, S, Bruna, A, Ardizzi, M, Bianchi, W, Bernardi |
| Rok vydání: |
1990 |
| Předmět: |
|
| Zdroj: |
Minerva medica. 81(4) |
| ISSN: |
0026-4806 |
| Popis: |
In standard clinical practice the pharmacokinetic profile of theophylline is monitored by measuring blood levels of the drug. However a more accurate picture of the metabolic pattern over time can be obtained by monitoring theophylline clearance. This technique was applied to 40 lung disease patients most (55%) of them slow metabolisers as described in the literature. In the light of this findings, cautious dosing is advisable when no data are available or clearance (difficult to apply outside a strictly specialist environment). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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