| Autor: |
Zhi-li, Guo, Ping, Liu, Yong-hong, Chen, Jian, Shang, Liubao, Zhang, Chunning, Sheng, Yun, Luo |
| Rok vydání: |
2004 |
| Předmět: |
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| Zdroj: |
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. 24(9) |
| ISSN: |
1003-5370 |
| Popis: |
To investigate the protective effect of mailuoning (MLN) on nerve cells after cerebral infarction induced by photochemistry.Eighty SD rats were divided into three groups, the control group (n = 20), the model group (n = 30) and the MLN group (n = 30). Focal cerebro-ischemia induced by photothrombosis in adult rat was used as a model. Changes of C-Fos protein expression before and after MLN treatment were observed using immunohistochemistry, computerized imaging technique and transmission electron microscopy (TEM).C-Fos positive cells located in the transitional zone between the necrotic core and normal cortex. C-Fos protein expression began to show 3 hrs after cerebral infarction, peaked at 6 hrs. As compared with the model group, C-Fos expression was significantly reduced in the MLN group (P0.01).MLN could markedly reduce the injury of nerve cell in the transitional zone, the protection may be related with its inhibition on C-Fos protein expression. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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