[Skin ulcerations due to CINCA syndrome and its successful treatment with prostaglandin E

Autor:	C, Brochhausen, M, Babel, V H, Schmitt, D, Grevenstein, S, Schreml, C, Meyer-Scholten, G, Klaus
Jazyk:	němčina
Rok vydání:	2018
Předmět:	Inflammasomes Interleukin-1beta Skin Ulcer Humans Female Alprostadil Cryopyrin-Associated Periodic Syndromes
Zdroj:	Zeitschrift fur Rheumatologie. 77(7)
ISSN:	1435-1250
Popis:	Chronic infantile neurological cutaneous and articular syndrome (CINCA) is a disorder with a defect in the CIAS1 (NLRP3) gene and the altered gene product cryopyrin leads to inflammasome activation with increased IL-1beta synthesis. The activation pathway of the transcription factor NF-κB is also affected, which plays a role in angiogenesis. With respect to the angiogenesis stimulating ability of prostaglandin E
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::13332dc0e2f6ff8916db68134ee63d1c https://pubmed.ncbi.nlm.nih.gov/30066026 Zobrazit plný text záznamu Full text from SpringerLink