Genotoxic and oxidative responses in coelomocytes of Eisenia fetida and Hediste diversicolor exposed to lipid-coated CdSe/ZnS quantum dots and CdCl2

Autor:	Gladys, Saez, Mélanie, Aye, Michel, De Meo, Ahissan, Aimé, Isabelle, Bestel, Philippe, Barthélémy, Carole, Di Giorgio
Rok vydání:	2013
Předmět:	Superoxide Dismutase Polychaeta Sulfides Thiobarbituric Acid Reactive Substances Oxidative Stress Selenium Cadmium Chloride Zinc Compounds Quantum Dots Leukocytes Animals Nanoparticles Comet Assay Oligochaeta Biomarkers DNA Damage Mutagens
Zdroj:	Environmental toxicology. 30(8)
ISSN:	1522-7278
Popis:	The emerging of Quantum Dots utilization in industrial or medicinal fields involved a potentially increase of these nanoparticles in environment. In this work, the genotoxic (comet assay) and oxidative effects (SOD activity, TBARS) of functionalized-QDs and cadmium chloride were investigated on Hediste diversicolor and Eisenia fetida coelomocytes. Results demonstrated that functionalized-QDs (QDNs) and cadmium chloride induced DNA damages through different mechanisms that depended on the nano- or ionic nature of Cd. The minimal genotoxic concentrations for H. diversicolor (0.001ng/g for QDNs and CdCl2 ) were lower than for E. fetida (between 0.01 and 0.1 ng/g for QDNs, and between 0.001 and 0.01 ng/g for CdCl2 ). These results showed that H. diversicolor was more sensitive than E. fetida. The two contaminants had a low impact on the oxidative stress markers.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::1317b50b4a6b23ec52dd6f8b8ec3ad14 https://pubmed.ncbi.nlm.nih.gov/24500942 Zobrazit plný text záznamu Plný text