Autor: |
Sushma, Pradeep, Shashank M, Patil, Chandan, Dharmashekara, Anisha, Jain, Ramith, Ramu, Prithvi S, Shirahatti, Subhankar P, Mandal, Pruthvish, Reddy, Chandrashekar, Srinivasa, Sharanagouda S, Patil, Joaqúın, Ortega-Castro, Juan, Frau, Norma, Flores-Holgúın, Chandan, Shivamallu, Shiva Prasad, Kollur, Daniel, Glossman-Mitnik |
Rok vydání: |
2022 |
Zdroj: |
Journal of biomolecular structuredynamics. |
ISSN: |
1538-0254 |
Popis: |
The spike (S) glycoprotein and nucleocapsid (N) proteins are the crucial pathogenic proteins of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) virus during its interaction with the host. Even FDA-approved drugs like dexamethasone and grazoprevir are not able to curb the viral progression inside the host and are reported with adverse effects on body metabolism. In this context, we aim to report corilagin a novel, potential dual inhibitor of S and N proteins from |
Databáze: |
OpenAIRE |
Externí odkaz: |
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