Molecular insights into the

Autor: Sushma, Pradeep, Shashank M, Patil, Chandan, Dharmashekara, Anisha, Jain, Ramith, Ramu, Prithvi S, Shirahatti, Subhankar P, Mandal, Pruthvish, Reddy, Chandrashekar, Srinivasa, Sharanagouda S, Patil, Joaqúın, Ortega-Castro, Juan, Frau, Norma, Flores-Holgúın, Chandan, Shivamallu, Shiva Prasad, Kollur, Daniel, Glossman-Mitnik
Rok vydání: 2022
Zdroj: Journal of biomolecular structuredynamics.
ISSN: 1538-0254
Popis: The spike (S) glycoprotein and nucleocapsid (N) proteins are the crucial pathogenic proteins of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) virus during its interaction with the host. Even FDA-approved drugs like dexamethasone and grazoprevir are not able to curb the viral progression inside the host and are reported with adverse effects on body metabolism. In this context, we aim to report corilagin a novel, potential dual inhibitor of S and N proteins from
Databáze: OpenAIRE