Diphenylethanediamine (DPEDA) as chiral selector: VII. Efficient HPLC resolution of a series of underivatized diarylcarbinols on a chiral stationary phase based on C5-amide-bonded N-3,5-dinitrobenzyl-DPEDA

Autor:	N M, Maier, G, Uray
Rok vydání:	1996
Předmět:	Dinitrobenzenes Binding Sites Molecular Structure Methanol Stereoisomerism Ethylenediamines Chromatography High Pressure Liquid
Zdroj:	Chirality. 8(7)
ISSN:	0899-0042
Popis:	Fast and efficient baseline separation of asymmetrically substituted diarylmethanols and 1,1-diarylethanols was achieved on an endcapped, amide-linked N-3,5-dinitrobenzoylated, (R,R)-1,2-diphenyl-1,2-ethanediamine-derived chiral stationary phase (CSP). Optimal enantioselectivities on this CSP were obtained using 1% 2-propanol in n-heptane as the mobile phase. Enantiorecognition was found to be governed by pi-basicity and the substitution pattern of the aromatic substituents.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::12ee9ccf4fcd26a3354dad90ac3fcc17 https://pubmed.ncbi.nlm.nih.gov/8970746 Zobrazit plný text záznamu Plný text