| Autor: |
A, Kurniawan, E, Sartono, W E, Setiowati, T, Supali, H, Wibowo, Purnomo, B, Rukmono, F, Partono |
| Rok vydání: |
1992 |
| Předmět: |
|
| Zdroj: |
The Southeast Asian journal of tropical medicine and public health. 23(2) |
| ISSN: |
0125-1562 |
| Popis: |
Clinical trials of Ivermectin in single oral doses of 200, 400, and 1,000 mg/kg body weight or in multiple doses of 200 mg/kg body weight for 5 consecutive days were performed in leaf monkeys (Presbytis cristatus) infected with Wuchereria kalimantani. Optimal microfilaricidal effect occurred at 200 mg/kg body weight. The drug was less effective than diethylcarbamazine in this animal model for human filariasis but had no adverse effects. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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