The D2 dopamine receptor gene as a predictor of compulsive disease: Bayes' theorem

Autor:	K, Blum, R C, Wood, E R, Braverman, T J, Chen, P J, Sheridan
Rok vydání:	1995
Předmět:	Cocaine Ethanol Attention Deficit Disorder with Hyperactivity Receptors Dopamine D2 Substance-Related Disorders Compulsive Behavior Brain Humans Bayes Theorem Feeding Behavior Severity of Illness Index Alleles
Zdroj:	Functional neurology. 10(1)
ISSN:	0393-5264
Popis:	The dopaminergic system, and in particular the dopamine D2 receptor, has been profoundly implicated in reward mechanisms in the meso-limbic circuitry of the brain. Dysfunction of the D2 dopamine receptors leads to aberrant substance (alcohol, drug, tobacco and food) seeking behavior. Decades of research indicate that genetics play an important role in vulnerability to severe substance seeking behavior. We propose that variants of the D2 dopamine receptor gene are important common genetic determinants in predicting compulsive disease.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::12c97167a94a62e9547ee9e24d1650e1 https://pubmed.ncbi.nlm.nih.gov/7649500 Zobrazit plný text záznamu